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黄安诚

助理教授

B栋415室
huangac@sustech.edu.cn

个人简介:

黄安诚博士于2014年底在澳大利亚阿德莱德大学获得天然产物化学博士学位。2015年在澳门科技大学中药质量国家重点实验室从事短暂工作后,获得欧盟玛丽居里个人奖金的资助在英国约翰英纳斯中心从事博士后工作,2019年8月全职回国加入南方科技大学生物系任助理教授。黄博士一直致力于植物代谢和天然产物研究。研究成果已发表在Science, PNAS和 Angew. Chem. In. Ed. 等国际主流期刊上,一作文章总影响因子85。

 

研究领域:

  • 天然产物生物合成途径发现与解析
  • 植物功能基因组学和代谢组学
  • 合成生物学和代谢工程
  • 酶学催化反应机理和酶工程改造
  • 小分子化合物介导的植物-微生物互作

 

工作经历:

2019.08 – 至今,南方科技大学生物系,助理教授

2015 – 2019,英国约翰英纳斯中心,博士后

2015,澳门科技大学中药质量控制国家重点实验室,博士后

 

学习经历:

2010-2014,澳大利亚阿德莱德大学,博士

2009-2010,华南理工大学,硕士研究生 

2005-2009,华南农业大学,学士

 

所获荣誉:

2016,欧盟玛丽居里学者

2014,阿德莱德大学院长卓越博士论文奖

2009, 华南农业大学‘红满堂’优秀本科生

 

代表文章:

1.Huang, A.C.#; Jiang, T.#; Liu, Y.X.; Bai, Y.C.; Reed, J.; Qu, B; Goossens, A.; Nutzmann, H.-W.; Bai, Y.; Osbourn, A. A specialized metabolic network selectively modulates Arabidopsis root microbiota. Science, 2019, 364(6440): eaau6389. (# Co-first author)

2.Huang, A.C., Osbourn, A. Plant terpenes that mediate below‐ground interactions: prospects for bioengineering terpenoids for plant protection. Pest Management Science, 2019, DOI:10.1002/ps.5410.

3.Huang, A.C.; Hong, Y. J.; Bond, A. D.; Tantillo, D. J.; Osbourn, A. Diverged terpene synthases reroute the carbocation cyclization path towards the formation of unprecedented 6/11/5 and 6/6/7/5 sesterterpene scaffolds. Angewandte Chemie International Edition, 2018, 57(5), 1291-1295.

4.Huang, A.C.; Kautsar S. A..; Hong, Y. J.; Bond, A. D.; Madema M. H.; Tantillo, D. J.; Osbourn, A. Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveal convergent evolution. Proceedings of the National Academy of Science, U.S.A., 2017, 114(29), E6005-6014.

5.Huang, A.-C.; Sefton, M. A.; Sumby, C. J.; Tiekink, E. R.T.; Taylor, D. K. Mechanistic studies on the autoxidation of a-guaiene: The structural diversity of the sesquiterpenoid downstream products. Journal of Natural Products, 2015, 78, 131-145.

6.Huang, A.-C.; Sefton, M. A.; Taylor, D. K. Comparison of the formation of peppery and woody sesquiterpenes derived from a-guaiene and a-bulnesene under aerial oxidative conditions. Journal of Agricultural and Food Chemistry, 2015, 63(8), 2137-2144

7.Huang, A.-C.; Sumby, C. J.; Tiekink, E. R.T.; Taylor, D. K. Synthesis of guaia-4(5)-en-11-ol, guaia-5(6)-en-11-ol, aciphyllene, 1-epi-melicodenone C and E and other guaiane-type sesquiterpenoids via the diastereoselective epoxidation of guaiol. Journal of Natural Products, 2014, 77(11), 2522-2536.

8.Huang, A.-C.; Burrett, S.; Sefton, M. A.; Taylor, D. K. Production of the pepper aroma compound, (-)-rotundone by aerial oxidation of α-guaiene. Journal of Agricultural and Food Chemistry, 2014, 62 (44), 10809–10815.

9.Huang, A.-C.; Wilde, A.; Ebmeyer, J.; Skouroumounis, G. K.; Taylor, D. K. Examination of the phenolic profile and antioxidant activity of the leaves of the Australian native plant Smilax glyciphylla. Journal of Natural Products, 2013, 76 (10), 1930-1936.

非一作文章:

10.Xue Z.; Tan Z.; Huang A.; Zhou Y.; Sun J.; Wang X.; Thimmappa R. B.; Stephenson M. J.; Osbourn A.; Qi X. Identification of key amino acid residues determining product specificity of 2,3-oxidosqualene cyclase in Oryza species. New Phytologist. 2018, 218(3):1076-1088.

11.Owen C.; Patron N. J.; Huang A.; Osbourn A. Harnessing plant metabolic diversity. Current Opinion in Chemical Biology, 2017, 40, 24-30.

12.Nützmann H.-W.; Huang A.; Osbourn A. Plant metabolic clusters-from genetics to genomics. New Phytologist. 2016, 211(3), 711-789.

13.Davies, C; Böttcher, C; Nicholson, E. L.; Burbidge, C. A.; Bastian, S; Harvey, K. E.; Huang, A.-C.; Taylor, D. K.; Boss, P. K. Shiraz wines made from grape berries (Vitis vinifera) delayed in ripening by plant growth regulator treatment have elevated rotundone levels and ‘pepper’ flavor and aroma. Journal of Agricultural and Food Chemistry, 2015, 63(8), 2137-2144.

 

联系方式:

深圳市南山区西丽学苑大道1088号南方科技大学B栋415室

邮编:518055

电子邮件:huangac@sustech.edu.cn

WELCOME TO BIOLOGY DEPARTMENT


  • 地址:

    广东省深圳市南山区学苑大道1088号
              南方科技大学第一科研楼2-3层

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