题 目：Expect the Unexpected: a tale of two Ion channels

主 讲：傅天民 助理教授

主 持：李颜颜 副教授

时 间：2024年8月8日（周四） 16:00-17:30

地 点：琳恩图书馆111报告厅

报告摘要：

In this talk, I will discuss the unexpected discoveries of two ion channels and highlight the exciting journey of an exceptional postdoc fellow. In the first story, I will tell you how we accidentally identified the first lysosomal proton channel when studying a non-canonical potassium channel. In my second story, I will elaborate how protein oligomerization can regulate the mechano-sensitivity of ion channels.

个人简介：

I received my Ph.D. from Peking University in 2011. Then, I joined Dr. Hao Wu’s lab at Harvard Medical School and worked on innate immune signaling from 2012 to 2020. My postdoctoral work focused on understanding of Death receptor signaling and inflammasomes. After starting my own lab in 2020 at the Ohio State University, I have shifted my focus to lysosomal signaling and bacterial immunity. Over the past four years, we have made a few groundbreaking discoveries in both fields and published our work in top-tier journals, including Nature, Cell, Mol Cell, and NSMB. Due to my contribution in cell signaling, I was named as a recipient of SCBA young investigator award, 2024.