题 目：Hypothalamic functions of Irx3 and Irx5 in metabolic regulation and obesity

主 讲：许志忠 教授

时 间：2022年1月12日16:10-17:30

腾讯会议 ：514-686-612

摘要:

Dr. Chi-chung Hui is Professor of Molecular Genetics at University of Toronto and Senior Scientist in the Program in Developmental & Stem Cell Biology of the Hospital for Sick Children Research Institute. He is also a Tier 1 Canada Research Chair in Mouse Development and Disease Modeling. His research focuses on Hedgehog signaling and Iroquois homeobox genes in development and disease. He published more than 150 research papers in leading journals including Nature, Cell, Science and New England Journal of Medicine. To date, his work has been cited close to 30,000 times with an h-index of 78.  In the past 2 decades, Dr. Hui is actively involved in promoting research and educational collaborations between Canada and China. He is an Honorary Professor in the School of Biomedical Science of the University of Hong Kong and an Executive Member of the Joint Institute of Genetics and Genome Medicine at Zhejiang University and University of Toronto. In recent years, his laboratory has been studying the functions of Irx3 and Irx5 in metabolic regulation and obesity. In this talk (Hypothalamic functions of Irx3 and Irx5 in metabolic regulation and obesity), he will discuss the hypothalamic functions of these two genes in neurogenesis and feeding regulation. 

个人介绍：

加拿大多伦多大学（University of Toronto）分子遗传学系教授兼国际合作高级顾问；病童医院（Hospital for Sick Children）研究所资深科学家兼国际合作负责人；加拿大政府高级研究领军人物（Tier 1 Canada Research Chair, 2016-2023）；Sanofi-Cell Research Outstanding Research Paper Award（2018）。一直是Sonic Hedgehog信号调控研究领域（生物学基础及医学）的领军人物；并开拓性地研究了Iroquois-class homeodomain proteins在高等动物发育，代谢调控，疾病发生中的作用。